Beyond Thalidomide: Birth defects explained.
نویسندگان
چکیده
منابع مشابه
Beyond Thalidomide - Birth Defects Explained
This book will appeal to the student of medical history and would be of interest to those entering general practice to obtain some insight into how their specialty evolved in modern times. The book is well written and scholarly and gives the reader a real sense of the evolutionary processes affecting general practice in the mid twentieth century with the foundation of the College of General Pra...
متن کاملRecognition of thalidomide defects.
Thalidomide: a brief history Thalidomide (alpha-phthalimido-glutarimide) was developed by the German firm Chemie Grunenthal as an anticonvulsant drug. Early trials showed it to be unsuitable for this purpose but indicated that it had sedative properties. Furthermore, it had one remarkable property: overdoses simply caused prolonged sleep, not death. The drug was first marketed in Germany in 195...
متن کاملOcular Defects in Thalidomide Babies.
IN the early reports on congenital abnormalities in thalidomide babies in Great Britain little attention has been paid to the occurrence of ocular defects. A recent survey by the Chief Medical Officer of the Ministry of Health relating to children born with congenital limb deformities during 1960-62, revealed that there were 652 surviving children with such deformities, 244 of whose mothers had...
متن کاملThalidomide: the tragedy of birth defects and the effective treatment of disease.
Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women. It became apparent in the 1960s that thalidomide treatment resulted in severe birth defects in thousands of children. Though the use of thalidomide was banned in most countries at that time, thalidomide proved to be a useful treatment for leprosy and later, multiple myeloma. In ru...
متن کاملEpidemiological Surveillance of Birth Defects Compatible with Thalidomide Embryopathy in Brazil
The thalidomide tragedy of the 1960s resulted in thousands of children being born with severe limb reduction defects (LRD), among other malformations. In Brazil, there are still babies born with thalidomide embryopathy (TE) because of leprosy prevalence, availability of thalidomide, and deficiencies in the control of drug dispensation. Our objective was to implement a system of proactive survei...
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ژورنال
عنوان ژورنال: The Journal of Bone and Joint Surgery. British volume
سال: 2008
ISSN: 0301-620X,2044-5377
DOI: 10.1302/0301-620x.90b9.21435